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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000378950 FEXAGRATINIB 200MG
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eMolecules 8-CHLORONAPHTHALEN-1-AMINE 5G
5000188155 8-CHLORONAPHTHALEN-1-AMINE 5G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000380574 ML281 200MG
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Sigma Aldrich Fine Chemicals Biosciences Q SepharoseR Xl Cytiva 17
Q Sepharose(R) XL is a strong anion exchanger designed for use in the capture steps of biomolecules from clarified feed-stocks.Q Sepharose(R) XL is based on a highly cross-linked bead formed 6% agarose matrix similar to the well established Q Sepharose(R) Fast Flow media. Dextran chains are covalently coupled to the agarose matrix and modified with quaternary ammonium (Q) strong anion exchange groups through chemically stable ether bonds. The stable agarose matrix and long flexible chains of dextran with bound charged groups work together to increase loading capacity whilst allowing high flow rates.With its high loading capacities and excellent physical and chemical stability Q Sepharose(R) XL is suitable for the capture stage of a downstream process which is characterised by large loads of crude samples.As member of the BioProcess media range Q Sepharose(R) XL meets industrial demands with security of supply and comprehensive technical and regulatory support.
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Medchemexpress LLC Guanidinoethyl sulfonate | 543-18-0 | 99.9% | 167.19 | 50 MG
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Guanidinoethyl sulfonate | 543-18-0 | 99.9% | 167.19 | 50 MG
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Medchemexpress LLC Orlistat | 96829-58-2 | 99.97% | 200 MG
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Orlistat (Tetrahydrolipstatin) is an irreversible inhibitor of pancreatic and gastric lipases, and fatty acid synthase (FASN). It is used orally for long-term research of obesity and exhibits an anti-atherosclerotic effect.
- Inhibits pancreatic and gastric lipases
- Inhibits fatty acid synthase (FASN)
- Used for long-term research of obesity
- Demonstrates anti-atherosclerotic effects
- Suitable for in vitro and in vivo studies
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Apexbio Technology LLC Cyclosporin A 59865-13-3 200mg
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Cyclosporin A is an immunosuppressive agent acting primarily through inhibition of cyclophilins intracellular peptidyl-prolyl isomerases with a reported IC50 of 7 nM Cyclophilins regulate mitochondrial permeability transition pore (MPTP) opening intracellular calcium signaling and NFAT transcriptional activation pathways Cyclosporin A s ability to inhibit calcineurin-NFAT signaling in T-cell activation leads to suppression of inflammatory immune responses indicating potential use in autoimmune disorder research Additionally it modulates cell apoptosis and survival mechanisms in diverse models including retinal ischemic injury viral entry (HBV HCV) and tumor biology in colon cancer cell lines
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Medchemexpress LLC Mycophenolate mofetil | 128794-94-5 | 99.8% | 200 MG
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Mycophenolate mofetil (RS 61443) is the morpholinoethylester proagent of Mycophenolic acid. It inhibits de novo purine synthesis by inhibiting inosine monophosphate dehydrogenase (IMPDH). Mycophenolate mofetil exhibits selective lymphocyte antiproliferative effects on both T and B cells, which prevents antibody formation.
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Medchemexpress LLC Zm241385 | 139180-30-6 | 99.5% | 337.34 | 200 MG
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Zm241385 | 139180-30-6 | 99.5% | 337.34 | 200 MG
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Medchemexpress LLC Dihydroergocristine (mesylate) | 24730-10-7 | 5 MG
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Dihydroergocristine mesylate (DHEC mesylate) is a γ-secretase (GSI) inhibitor. It is known for its ability to reduce the production of Alzheimer's disease amyloid-β peptides by binding directly to γ-secretase and Nicastrin.
- Inhibits γ-secretase (GSI)
- Reduces production of amyloid-β peptides
- Binds directly to γ-secretase and Nicastrin with Kd values of 25.7 nM and 9.8 μM, respectively
- Exhibits an IC50 value of 25 μM for inhibiting γ-secretase activity in T100 cells without affecting cell viability
- Inhibits cellular Aβ production
- Causes dose-dependent accumulation of carboxy-terminal fragments of APP (APP-CTFs) in HEK293
- Decreases γ-secretase activity in fibroblast cells
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Medchemexpress LLC (S,R,S)-AHPC-amido-C5-acid | 2162120-87-6 | 572.72 | 100 MG
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This product is (S,R,S)-AHPC-amido-C5-acid, a solid laboratory chemical identified as an E3 Ligase Ligand-Linker Conjugate involved in PROTAC design. It is used in the manufacture of various substances and for research purposes.
- Harmful if swallowed
- Causes skin irritation
- Causes serious eye irritation
- May cause respiratory irritation
- Stable under recommended storage conditions
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Medchemexpress LLC Insulin (human) | 11061-68-0 | 99.9% | 5807.57 | 200 MG
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Insulin (human) is a polypeptide hormone vital for regulating glucose levels in the body, primarily used in the treatment of diabetes mellitus. This product is a recombinant human insulin, a synthetic version of the hormone, and appears as a white to off-white solid. The human insulin gene contains specific intervening sequences, one within the 5'-untranslated segment of the mRNA and another interrupting the C-peptide encoding region, which are important for its biological function.
- Regulates glucose levels
- Used for diabetes mellitus treatment
- Recombinant human insulin
- White to off-white solid appearance
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000431319 1 4-DICHLORO 5-CARBO 50MG
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Medchemexpress LLC 4-Quinolinol | 611-36-9 | 99.9% | C9H7NO | 1 ML
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4-Quinolinol (Kynurine) is a quinoline derivative that modulates tryptophan metabolism through the Kynurine pathway, involved in neuroprotective effects. It promotes tumor cell survival and motility by suppressing antitumor immune responses, particularly active in human brain tumors where AhR activation enhances TDO expression, producing more kynurine and kynurinic acid.
- Quinoline derivative
- Modulates tryptophan metabolism
- Involved in neuroprotective effects
- Promotes tumor cell survival and motility
- Suppresses antitumor immune responses
- Soluble in DMSO (100 mg/mL)
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Medchemexpress LLC Chlorphenesin | 104-29-0 | MFCD00021990 | 99.8% | C9H11ClO3 | 200 MG
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Chlorphenesin is a reversible antigen-associated immunosuppressant with antibacterial and antifungal properties, commonly used in eye care cosmetics. It is intended for research use only.
- Reduces Akt pathway activity in human meibomian gland epithelial cells
- Induces rounding and atrophy of immortalized HMGECs
- Leads to reduced number of immortalized HMGECs
- Functions as an antibacterial agent
- Functions as an antifungal agent
- Utilized in eye care cosmetics
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