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Filtered Search Results
Ambeed Dicyclohexyl 2 6 diisopropoxy
Dicyclohexyl(2',6'-diisopropoxy-[1,1'-biphenyl]-2-yl)phosphine, 787618-22-8, 97%
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Medchemexpress LLC Benzyl-PEG2-amine | 1268135-96-1 | C11H17NO2 | 1 G
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Benzyl-PEG2-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Connects ligands for E3 ubiquitin ligase and target proteins
- Utilizes the ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC Peg-bis-amine (MW 2000) | 24991-53-5 | 99.4% | (C2H4O)nC4H12N2O | 250 MG
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PEG-bis-amine (Poly(ethylene glycol)-bis-amine) (MW 2000) is a PEG-based PROTAC linker. It is used in the synthesis of PROTACs, which are molecules designed to exploit the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- Can be used in the synthesis of PROTACs
- PROTACs contain two different ligands connected by a linker
- Ligands are for an E3 ubiquitin ligase and a target protein
- PROTACs exploit the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC MPEG-amine (MW 20000) | 80506-64-5 | 98.0% | (C2H4O)nC3H9NO | 250 MG
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MPEG-amine (MW 20000) is a PEG-based PROTAC linker, crucial for the synthesis of PROTACs. These PROTACs are innovative molecules that utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins, featuring two distinct ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other for the target protein.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits ubiquitin-proteasome system to degrade target proteins
- Average molecular weight of 20000
- Appears as a solid
- Color is white to off-white
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Apexbio Technology LLC Bindarit 130641-38-2 200mg
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Bindarit (CAS 130641-38-2) also known as AF-2838 is a synthetic small-molecule inhibitor targeting the CC chemokines MCP-1 (CCL2) MCP-2 (CCL8) and MCP-3 (CCL7) By suppressing the transcription and production of MCP proteins Bindarit reduces monocyte chemoattraction and inflammation In vitro data indicate that Bindarit inhibits LPS-induced MCP-1 synthesis in monocytes with an IC50 around 172 M and selectively decreases MCP expression without impacting unrelated cytokines such as IL-6 or IL-8 Animal studies demonstrate its potential to reduce inflammatory cell infiltration vascular smooth muscle cell proliferation and neointimal hyperplasia in rodent injury models highlighting its value for inflammation and cardiovascular disease research
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Ambeed 3 2Hydroxyethoxy propanoic aci
3-(2-Hydroxyethoxy)propanoic acid, 89211-34-7, 95%
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Ambeed Bis 2ethylhexyl terephthalate
Bis(2-ethylhexyl) terephthalate, 6422-86-2, 98%
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Ambeed 4 Benzyloxy phenyl boronic ac
(4-(Benzyloxy)phenyl)boronic acid, 146631-00-7, 98%
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Ambeed 3Aminopiperidine2 6dione
3-Aminopiperidine-2,6-dione, 2353-44-8, 98%
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Ambeed 4Aminoisophthalic acid
4-Aminoisophthalic acid, 33890-03-8, 98%
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Ambeed tertButyl 3 8diazabicyclo 3.2.
tert-Butyl 3,8-diazabicyclo[3.2.1]octane-8-carboxylate, 149771-44-8, 96%
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Ambeed 2 4DibromoN 4bromophenyl N 2 4
2,4-Dibromo-N-(4-bromophenyl)-N-(2,4-dibromophenyl)aniline, 73087-81-7, 95%
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Medchemexpress LLC DBCO-amine | 1255942-06-3 | 99.1% | 276.34 g·mol-1 | C18H16N2O | 25 MG
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DBCO-amine is a dibenzocyclooctyne-containing amine reagent used for strain-promoted alkyne-azide cycloaddition (SPAAC) click chemistry. It is used as a small linker for bioconjugation and the synthesis of antibody-drug conjugates, and is typically handled and stored under anhydrous conditions and in organic solvent solutions for formulation.
- Enables strain-promoted alkyne-azide cycloaddition (SPAAC) bioconjugation.
- High purity suitable for synthetic and bioconjugation applications.
- Minimal spacer length reduces steric hindrance in conjugates.
- Compatible with common coupling chemistries for linker installation.
- Soluble in DMSO for straightforward formulation and handling.
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Ambeed Ni dtbbpy H2O 4 Cl2
[Ni(dtbbpy)(H2O)4]Cl2, 2035424-75-8, 98%
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eMolecules 8-Hydroxyquinoline-beta-D-glucuronic acid, sodium salt | 207728-71-0 | MFCD02683911 | 1g
Apollo Scientific | 8-Hydroxyquinoline-beta-D-glucuronic acid, sodium salt | 1g | 562462588 | BIB6070 | | 207728-71-0 | MFCD02683911 | 343.267 | C15H14NNaO7
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